- Home ›
- Publications
Publications
- Dai J., Patzke C., Liakath-Ali K., Seigneur E., and Südhof T.C. GluD1 is a signal transduction device disguised as an ionotropic receptor. Nature 2021 Jul;595(7866):261-265. doi: 10.1038/s41586-021-03661-6.
-
Patzke C.+*, Dai J+, Brockmann M.M.+, Sun Z., Fenske P., Rosenmund C., Südhof T.C. Cannabinoid receptor activation acutely increases synaptic vesicle numbers by activating Synapsins in human synapses. Molecular Psychiatry. 2021 Apr 30. doi: 10.1038/s41380-021-01095-0. +contributed equally, *single corresponding author
- Mencacci N.E., Brockmann M.M., Dai J., Pajusalu S., Atasu B., Campos J., Pino G., Gonzalez-Latapi P., Patzke, C. Schwake M., et al. Biallelic variants in TSPOAP1, encoding the active-zone protein RIMBP1, cause autosomal recessive dystonia. The Journal of Clinical Investigation. 2021 Apr 1;131(7):e140625. doi: 10.1172/JCI140625.
-
Patzke C.+*, Brockmann M.M.+, Dai J.+, Gan K.J., Grauel M.K., Fenske P., Liu Y., Acuna C., Rosenmund C., Südhof T.C. Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses, Cell, Oct 3;179(2):498-513.e22. doi: 10.1016/j.cell.2019.09.011. +contributed equally, *single corresponding author
- Zhang Z., Marro S.G., Zhang Y, Arendt K.L., Patzke C., Zhou B., Fair T., Yang N., Südhof T.C., Wernig M., Chen L. The Fragile-X Mutation Impairs Homeostatic Plasticity in Human Neurons by Blocking Synaptic Retinoic Acid Signaling. Science Translational Medicine. 2018 Aug 1; 10, eaar4338. doi: 10.1126/scitranslmed.aar4338
-
Patzke C.*, Südhof T.C. (2016): The conditional KO approach: Cre/Lox technology in human neurons (Mini Review). Rare Diseases. 2016 Feb 18;4(1):e1131884. doi: 10.1080/21675511.2015.1131884. *single corresponding author
-
Patzke C.*, Acuna C., Giam L., R., Wernig M., Südhof T.C. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. The Journal of Experimental Medicine. 2016 Apr 4;213(4):499-515. doi: 10.1084/jem.20150951. *single corresponding author
- Yi F., Danko T., Botelho S.C., Patzke C., Pak C., Wernig M., Südhof T.C. Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons. Science. 2016 May 6;352(6286):aaf2669. doi: 10.1126/science.aaf2669.
-
Patzke C.+*, Han+ Y., Covy J., Yi F., Maxeiner S., Wernig M., and Südhof T.C. Analysis of conditional heterozygous STXBP1 mutations in human neurons. The Journal of Clinical Investigation 2015 Sep;125(9):3560-71. doi: 10.1172/JCI78612. +contributed equally, *single corresponding author
- Zhang Y., Pak C., Han Y., Ahlenius H., Zhang Z., Chanda S., Marro S., Patzke C., Acuna C., Covy J., Xu W., Yang N., Danko T., Chen L., Wernig M., Südhof T.C. (2013). Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron 2013 Jun 5;78(5):785-98. doi: 10.1016/j.neuron.2013.05.029.
-
Patzke C., Max K., Behlke J., Schreiber J., Schmidt H., Dorner A., Kröger S., Henning M., Otto A., Heinemann U. and Rathjen F.G. (2010). The Coxsackie-Adenovirus receptor (CAR) reveals complex homophilic and heterophilic binding activities on neural cells. Journal of Neuroscience 2010 Feb 24;30(8):2897-910. doi: 10.1523/JNEUROSCI.5725-09.2010.